CCDC71

Across TCGA cell cohorts, CCDC71 mutation is significantly associated with the drug of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC71-associated genes across cancer lineages are Pevonedistat, AKT inhibitor VIII, and 776928. Each is linked with CCDC71 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC71-to-partner and partner-to-CCDC71 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pevonedistat grouped by CCDC71-low versus CCDC71-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC71→partner) and Y-score (partner→CCDC71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Pevonedistat →	+0.770	+2.649	.025	.046	3	1
LARGE_INTESTINE	AKT inhibitor VIII →	+0.407	+2.667	.045	.040	3	1
LARGE_INTESTINE	776928 →	+0.615	+2.871	.040	.021	3	1
LARGE_INTESTINE	BPD-00008900 →	+0.464	+2.655	.020	.044	3	1
LARGE_INTESTINE	Tubastatin A →	+0.417	+2.874	.009	.021	3	1
LARGE_INTESTINE	KIN001-236 →	+0.371	+2.874	.005	.021	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Pevonedistat by CCDC71 expression — LARGE_INTESTINE

Explore this box plot interactively →