CCDC71

Across TCGA pan-cancer cohorts, CCDC71 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated CCDC71 data layer compared with 3 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in uveal melanoma (UVM), where higher CCDC71 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CCDC71 expression acts as an unfavorable survival marker, although some lineages such as UVM and KIRC show a favorable association.

UVM, LIHC, and KICH are the cancer types where CCDC71 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Median	All	0.761	0.425	<.001	83	view →
LIHC	DFS	Tertile	All	0.330	0.506	<.001	67	view →
KICH	DFS	Tertile	All	0.745	1.000	.009	52	view →
KIRC	DFS	Quartile	All	0.843	0.450	<.001	50	view →
BRCA	OS	Median	III,IV	0.956	0.851	<.001	42	view →
LUAD	DFS	Tertile	III,IV	0.516	0.180	.009	30	view →
ACC	DFS	Tertile	II,III,IV	0.250	0.716	.001	28	view →
SKCM	DFS	Quartile	All	0.689	0.883	.005	20	view →
READ	DFS	Median	All	0.894	0.570	.002	19	view →
MESO	DFS	Quartile	IV	0.242	0.886	.010	18	view →
KIRP	DFS	Tertile	II,III,IV	0.723	0.307	.008	15	view →
CHOL	OS	Quartile	II,III,IV	1.000	0.384	.028	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

CCDC71–UVM (OS)

Open the UVM breakdown →