CCDC71

Across TCGA pan-cancer cohorts, CCDC71 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of CCDC71’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where CCDC71 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC71 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

LIHC, KICH, and THCA are the cancer types where CCDC71 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC71 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	III,IV	+0.763	<.001	9	view →
KICH	Male	All	−1.160	<.001	8	view →
THCA	Male	III,IV	−0.655	<.001	8	view →
KIRC	Male	II,III,IV	−0.491	<.001	8	view →
LUSC	All	All	−0.222	.002	5	view →
COAD	Female	All	+0.401	.006	4	view →
CHOL	Male	All	+1.221	<.001	3	view →
UCEC	All	All	−0.344	.040	2	view →
STAD	Male	II,III,IV	+0.378	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

CCDC71–LIHC

Open the LIHC breakdown →