CCDC68

Across TCGA patient cohorts, CCDC68 mutation is significantly associated with the RNA expression of many other genes, with 2,752 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC68-associated genes across cancer lineages are DSCR4, OR1B1, and RRP9. Each is linked with CCDC68 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC68-to-partner and partner-to-CCDC68 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DSCR4 grouped by CCDC68-low versus CCDC68-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC68→partner) and Y-score (partner→CCDC68) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	DSCR4 →	+0.690	+3.920	.002	.007	3	3
CESC	OR1B1 →	+0.042	+7.584	<.001	<.001	3	2
SKCM	RRP9 →	+0.492	+3.227	<.001	<.001	3	2
SKCM	ITGB1BP1 →	+0.485	+2.534	<.001	.001	3	2
SKCM	ENPP2 →	-1.419	-2.897	<.001	.001	3	2
UCEC	TCF19 →	+0.692	+2.329	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,752 associations by consensus.

DSCR4 by CCDC68 expression — LUSC

Explore this box plot interactively →