CCDC68

Across TCGA cell cohorts, CCDC68 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,679 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CCDC68-associated GO terms across cancer lineages are Cellular response to environmental stimulus, Cellular response to abiotic stimulus, and Vacuolar transport. Each is linked with CCDC68 in more than 9 cancer types. Because this analysis shows association rather than direction, both CCDC68-to-partner and partner-to-CCDC68 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to environmental stimulus grouped by CCDC68-low versus CCDC68-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC68→partner) and Y-score (partner→CCDC68) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cellular response to environmental stimulus →	+0.047	+1.394	.002	.004	3	9
BONE	Cellular response to abiotic stimulus →	+0.047	+1.394	.002	.004	3	9
LIVER	Vacuolar transport →	+0.050	+2.415	.007	<.001	2	10
LUNG_NSCLC_LUSC	Hepatocyte growth factor receptor signaling pathway →	+0.227	+2.620	.002	.001	3	8
BLOOD_Myeloma	Establishment of protein localization to vacuole →	+0.056	+0.032	<.001	.005	3	8
LARGE_INTESTINE	Endosome to lysosome transport →	+0.061	+1.132	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,679 associations by consensus.

Cellular response to environmental stimulus by CCDC68 expression — BONE

Explore this box plot interactively →