CCDC61

Across TCGA cell cohorts, CCDC61 mutation is significantly associated with the mutation status of many other genes, with 1,525 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC61-associated genes across cancer lineages are POU5F1B, INPP4A, and SLC24A1. Each is linked with CCDC61 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC61-to-partner and partner-to-CCDC61 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, POU5F1B grouped by CCDC61-low versus CCDC61-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC61→partner) and Y-score (partner→CCDC61) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	POU5F1B →	+4.415	+4.977	.007	.007	1	3
OVARY	INPP4A →	+4.415	+4.977	.007	.007	1	3
LARGE_INTESTINE	SLC24A1 →	+2.936	+4.471	.001	.001	1	3
OVARY	SH3PXD2A →	+5.415	+5.415	.004	.004	1	3
LARGE_INTESTINE	TRPM6 →	+2.043	+3.693	.009	.009	1	3
LARGE_INTESTINE	MARF1 →	+2.159	+3.807	.007	.007	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,525 associations by consensus.

POU5F1B by CCDC61 expression — OVARY

Explore this box plot interactively →