CCDC54

Across TCGA patient cohorts, CCDC54 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,690 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CCDC54-associated proteins across cancer lineages are TGFB1I1_S216, ARID3A_S119, and SET. Each is linked with CCDC54 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC54-to-partner and partner-to-CCDC54 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC54 versus TGFB1I1_S216 in HNSC, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC54→partner) and Y-score (partner→CCDC54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TGFB1I1_S216 →	+0.830	+0.330	.001	.006	3	3
LUAD	ARID3A_S119 →	-0.751	-0.220	<.001	<.001	3	3
OV	SET →	-0.422	-0.264	<.001	<.001	3	3
PDAC	C1orf198_S289 →	+0.476	+0.418	<.001	<.001	3	3
OV	HIC1_S237 →	+1.192	+0.309	<.001	<.001	3	3
OV	KANK2 →	+0.314	+0.179	.005	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,690 associations by consensus.

CCDC54 vs TGFB1I1_S216 — HNSC

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