CCDC3

Across TCGA cell cohorts, CCDC3 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CCDC3-associated genes across cancer lineages are RBMY1F, OR13G1, and PTH. Each is linked with CCDC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC3-to-partner and partner-to-CCDC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBMY1F grouped by CCDC3-low versus CCDC3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC3→partner) and Y-score (partner→CCDC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	RBMY1F →	+0.221	+4.887	<.001	.009	3	2
LARGE_INTESTINE	OR13G1 →	+0.032	+5.415	<.001	.004	3	1
LUNG_NSCLC_LUAD	PTH →	+0.031	+4.887	<.001	.009	3	1
STOMACH	PIGY →	+0.929	+4.432	<.001	.003	3	1
SKIN	SMIM36 →	+0.204	+4.977	<.001	.007	3	1
SKIN	C7orf77 →	+0.148	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

RBMY1F by CCDC3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →