CCDC27

Across TCGA cell cohorts, CCDC27 mutation is significantly associated with the RNA expression of many other genes, with 514 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC27-associated genes across cancer lineages are OR56A4, OR56A1, and VN1R2. Each is linked with CCDC27 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC27-to-partner and partner-to-CCDC27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR56A4 grouped by CCDC27-low versus CCDC27-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC27→partner) and Y-score (partner→CCDC27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR56A4 →	+0.176	+5.362	<.001	<.001	3	2
LUNG_NSCLC_LUAD	OR56A1 →	+0.315	+4.189	<.001	.002	3	1
LUNG_NSCLC_LUAD	VN1R2 →	+0.036	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	IQCF3 →	+0.029	+4.813	<.001	<.001	3	1
LUNG_NSCLC_LUAD	GYPB →	+0.082	+3.544	<.001	.009	3	1
STOMACH	CT47A6 →	+0.046	+5.285	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 514 associations by consensus.

OR56A4 by CCDC27 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →