CCDC24

Across TCGA patient cohorts, CCDC24 mutation is significantly associated with the RNA expression of many other genes, with 373 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC24-associated genes across cancer lineages are MIR5583-1, MIR5579, and IGKV2OR2-8. Each is linked with CCDC24 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC24-to-partner and partner-to-CCDC24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5583-1 grouped by CCDC24-low versus CCDC24-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC24→partner) and Y-score (partner→CCDC24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR5583-1 →	+0.564	+5.332	<.001	.002	3	2
BLCA	MIR5579 →	+0.544	+5.251	<.001	.006	3	1
BLCA	IGKV2OR2-8 →	+0.127	+5.251	.007	.006	3	1
UCEC	BTBD10 →	+0.539	+2.743	.003	.003	3	1
UCEC	ADGRL3 →	+1.130	+2.608	<.001	.006	3	1
UCEC	BAG3 →	+0.816	+3.234	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 373 associations by consensus.

MIR5583-1 by CCDC24 expression — COAD

Explore this box plot interactively →