CCDC24

Across TCGA pan-cancer cohorts, CCDC24 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated CCDC24 data layer compared with 3 for mutation status.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher CCDC24 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CCDC24 expression acts as an unfavorable survival marker, although some lineages such as BRCA and HNSC show a favorable association.

BRCA, KIRC, and HNSC are the cancer types where CCDC24 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.627	0.526	<.001	92	view →
KIRC	DFS	Quartile	All	0.711	0.852	<.001	74	view →
HNSC	OS	Quartile	All	0.823	0.620	<.001	68	view →
BLCA	DFS	Median	II,III,IV	0.587	0.447	.002	66	view →
LIHC	DFS	Quartile	All	0.407	0.614	<.001	65	view →
ACC	DFS	Tertile	All	0.198	0.712	<.001	56	view →
LGG	DFS	Median	All	0.260	0.491	<.001	47	view →
UCS	OS	Tertile	IV	0.311	0.844	.024	20	view →
STAD	DFS	Quartile	III,IV	0.909	0.464	.001	15	view →
ESCA	DFS	Tertile	All	0.894	0.320	.019	12	view →
CHOL	OS	Median	All	0.757	0.284	.023	12	view →
COAD	OS	Median	IV	0.809	0.492	.018	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

CCDC24–BRCA (OS)

Open the BRCA breakdown →