CCDC24

Across TCGA pan-cancer cohorts, CCDC24 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of CCDC24’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where CCDC24 RNA is repressed in tumor relative to normal tissue. In most cancer types CCDC24 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, COAD, and HNSC are the cancer types where CCDC24 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC24 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−1.693	<.001	11	view →
COAD	Female	All	+0.671	<.001	10	view →
HNSC	Male	III,IV	+1.457	<.001	8	view →
LIHC	Female	II,III,IV	+1.171	<.001	8	view →
STAD	All	II,III,IV	+0.848	<.001	8	view →
LUAD	All	II,III,IV	+0.562	<.001	7	view →
BLCA	Female	III,IV	+1.054	.014	6	view →
BRCA	All	III,IV	+0.993	<.001	6	view →
THCA	Male	III,IV	−0.767	<.001	6	view →
CHOL	All	All	+2.606	<.001	5	view →
ESCA	All	All	+0.978	.009	4	view →
KIRC	All	All	−0.339	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

CCDC24–KICH

Open the KICH breakdown →