CCDC24

Across TCGA cell cohorts, CCDC24 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC24-associated genes across cancer lineages are CFC1, SMR3B, and MRGPRX4. Each is linked with CCDC24 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC24-to-partner and partner-to-CCDC24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFC1 grouped by CCDC24-low versus CCDC24-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC24→partner) and Y-score (partner→CCDC24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CFC1 →	+0.022	+5.539	<.001	.003	3	1
BLOOD_Leukemia	SMR3B →	+0.047	+4.922	<.001	.009	3	1
BLOOD_Leukemia	MRGPRX4 →	+0.018	+4.922	<.001	.009	3	1
LARGE_INTESTINE	OR11A1 →	+0.021	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CFC1 by CCDC24 expression — BLOOD_Leukemia

Explore this box plot interactively →