CCDC182

Across TCGA cell cohorts, CCDC182 RNA expression is significantly associated with the go_rna of many other GO terms, with 712 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC182-associated GO terms across cancer lineages are Regulation of cell fate specification, Regulation of transcription of nucleolar large rRNA by RNA polymerase I, and Positive regulation of inflammatory response to wounding. Each is linked with CCDC182 in more than 4 cancer types. Because this analysis shows association rather than direction, both CCDC182-to-partner and partner-to-CCDC182 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell fate specification grouped by CCDC182-low versus CCDC182-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC182→partner) and Y-score (partner→CCDC182) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of cell fate specification →	+0.103	+0.035	.002	.005	3	5
BLOOD_Leukemia	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.051	+0.296	.001	.009	3	4
BLOOD_Leukemia	Positive regulation of inflammatory response to wounding →	+0.125	+0.323	.005	.007	3	3
BLOOD_Leukemia	N-acetylglucosamine metabolic process →	-0.065	-0.323	<.001	<.001	3	3
BLOOD_Leukemia	Placenta blood vessel development →	+0.125	+0.329	<.001	<.001	3	3
BLOOD_Leukemia	Heart formation →	+0.138	+0.347	.002	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 712 associations by consensus.

Regulation of cell fate specification by CCDC182 expression — LUNG_SCLC

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