CCDC182

Across TCGA pan-cancer cohorts, CCDC182 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated CCDC182 data layer compared with 1 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CCDC182 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CCDC182 expression acts as an unfavorable survival marker, although some lineages such as LUAD and KIRP show a favorable association.

LUAD, LGG, and THYM are the cancer types where CCDC182 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.754	0.638	.010	48	view →
LGG	OS	Median	All	0.731	0.875	<.001	48	view →
THYM	DFS	Quartile	II,III,IV	0.719	0.974	.012	34	view →
KIRP	DFS	Tertile	All	1.000	0.817	.009	29	view →
SKCM	OS	Tertile	II,III,IV	0.897	0.249	.001	27	view →
DLBC	DFS	Tertile	II,III,IV	0.433	0.944	.008	27	view →
UCEC	OS	Tertile	III,IV	0.443	0.666	.025	24	view →
LUSC	DFS	Tertile	III,IV	0.363	0.788	.002	18	view →
UCS	DFS	Tertile	IV	0.318	0.745	.042	18	view →
COAD	DFS	Tertile	III,IV	0.313	0.631	.021	18	view →
ACC	OS	Quartile	III,IV	0.425	0.806	.004	13	view →
READ	OS	Tertile	II,III,IV	0.652	0.926	.024	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

CCDC182–LUAD (DFS)

Open the LUAD breakdown →