Across TCGA pan-cancer cohorts, CCDC182 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of CCDC182’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where CCDC182 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC182 is over-expressed in tumor.
KIRP, KIRC, and THCA are the cancer types where CCDC182 tumor–normal differential expression is most reproducible.