CCDC181

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC181 protein abundance is significantly associated with the RNA expression of many other genes, with 1,678 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC181-associated genes across cancer lineages are RSPH14, SPEF1, and TSNAXIP1. Each is linked with CCDC181 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC181-to-partner and partner-to-CCDC181 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC181 versus RSPH14 in LUAD, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC181→partner) and Y-score (partner→CCDC181) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADRSPH14 →+0.462+0.853<.001<.00132
LSCCSPEF1 →+0.614+1.410<.001<.00132
LUADTSNAXIP1 →+0.498+1.261.004<.00132
LUADCCDC114 →+0.860+1.405<.001<.00132
LSCCCAPS →+0.840+1.021<.001<.00132
LUADLRRC23 →+0.517+0.721<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,678 associations by consensus.

CCDC181 vs RSPH14 — LUAD

Per-sample scatter of CCDC181 vs RSPH14 in LUAD (Pearson r = 0.51).

Explore this scatter interactively →

Exploration