CCDC181

Across TCGA cell cohorts, CCDC181 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,947 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CCDC181-associated GO terms across cancer lineages are Protein-RNA complex organization, Protein-RNA complex assembly, and RNA splicing, via transesterification reactions. Each is linked with CCDC181 in more than 11 cancer types. Because this analysis shows association rather than direction, both CCDC181-to-partner and partner-to-CCDC181 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-RNA complex organization grouped by CCDC181-low versus CCDC181-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC181→partner) and Y-score (partner→CCDC181) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein-RNA complex organization →	+0.088	+1.125	<.001	<.001	3	12
BONE	Protein-RNA complex assembly →	+0.090	+1.155	<.001	<.001	3	12
SKIN	RNA splicing, via transesterification reactions →	+0.067	+1.364	<.001	<.001	3	12
SKIN	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.066	+1.205	<.001	<.001	3	12
SKIN	mRNA splicing, via spliceosome →	+0.066	+1.205	<.001	<.001	3	12
STOMACH	Translational initiation →	+0.101	+1.474	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,947 associations by consensus.

Protein-RNA complex organization by CCDC181 expression — BONE

Explore this box plot interactively →