CCDC14

Across TCGA patient cohorts, CCDC14 mutation is significantly associated with the RNA expression of many other genes, with 2,894 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC14-associated genes across cancer lineages are RNU6-391P, TMX2P1, and PDHX. Each is linked with CCDC14 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC14-to-partner and partner-to-CCDC14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-391P grouped by CCDC14-low versus CCDC14-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC14→partner) and Y-score (partner→CCDC14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-391P →	+0.199	+4.842	<.001	.002	3	3
COAD	TMX2P1 →	+0.491	+3.335	.007	.005	3	3
UCEC	PDHX →	+0.479	+1.701	<.001	<.001	3	3
UCEC	DHDDS →	+0.269	+1.648	.002	.001	3	3
COAD	RPA2 →	+0.782	+3.375	<.001	.005	3	3
UCEC	ZWINT →	+0.746	+2.099	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,894 associations by consensus.

RNU6-391P by CCDC14 expression — CESC

Explore this box plot interactively →