Across TCGA patient cohorts, CCDC137 mutation is significantly associated with the RNA expression of many other genes, with 88 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC137-associated genes across cancer lineages are MRPS18CP4, JPT1P1, and CDY8P. Each is linked with CCDC137 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC137-to-partner and partner-to-CCDC137 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC137→partner) and Y-score (partner→CCDC137) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MRPS18CP4 →	+0.308	+3.286	<.001	.003	3	2
UCEC	JPT1P1 →	+0.296	+3.582	.003	.009	3	2
LUSC	CDY8P →	+0.029	+7.924	<.001	.008	3	2
LIHC	FAM74A4 →	+0.021	+5.355	<.001	.005	3	1
LIHC	TEX44 →	+0.261	+5.033	<.001	.009	3	1
LIHC	RNU6-600P →	+0.340	+5.878	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

Exploration

CCDC137 survival (RNA) · tumor vs normal (RNA) · all CCDC137 data types