Across TCGA patient cohorts, CCDC125 mutation is significantly associated with the RNA expression of many other genes, with 1,171 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC125-associated genes across cancer lineages are PHKG1P4, NANOGNBP3, and CCL5. Each is linked with CCDC125 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC125-to-partner and partner-to-CCDC125 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC125→partner) and Y-score (partner→CCDC125) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PHKG1P4 →	+0.140	+4.771	<.001	.006	3	2
UCEC	NANOGNBP3 →	-0.217	-2.615	.009	.006	3	1
UCEC	CCL5 →	+0.975	+2.454	<.001	<.001	3	1
UCEC	LINC02550 →	-0.386	-2.609	.007	.005	3	1
UCEC	KRT8P49 →	+0.191	+3.892	.001	<.001	3	1
UCEC	LINC01607 →	-0.602	-3.066	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,171 associations by consensus.

Exploration

CCDC125 survival (RNA) · tumor vs normal (RNA) · all CCDC125 data types