CCDC103

Across TCGA patient cohorts, CCDC103 mutation is significantly associated with the RNA expression of many other genes, with 3,121 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC103-associated genes across cancer lineages are RNU6-23P, HMGB3P3, and FKBP4P2. Each is linked with CCDC103 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC103-to-partner and partner-to-CCDC103 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-23P grouped by CCDC103-low versus CCDC103-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC103→partner) and Y-score (partner→CCDC103) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-23P →	+0.368	+2.382	<.001	<.001	3	3
UCEC	HMGB3P3 →	+0.194	+2.436	<.001	<.001	3	2
SKCM	FKBP4P2 →	+0.035	+5.037	.003	.009	3	1
SKCM	SELENOTP2 →	+0.117	+5.097	<.001	.008	3	1
SKCM	RNU6-92P →	+0.349	+4.979	<.001	.009	3	1
UCEC	NSUN3 →	+0.393	+3.608	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,121 associations by consensus.

RNU6-23P by CCDC103 expression — UCEC

Explore this box plot interactively →