CCDC103

Across TCGA pan-cancer cohorts, CCDC103 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated CCDC103 data layer compared with 5 for mutation status.

The strongest signal is observed in brain lower grade glioma (LGG), where higher CCDC103 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCDC103 expression acts as an unfavorable survival marker, although some lineages such as KIRC and MESO show a favorable association.

LGG, KIRC, and CHOL are the cancer types where CCDC103 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Median	All	0.665	0.805	<.001	47	view →
KIRC	DFS	Tertile	III,IV	0.619	0.283	.005	37	view →
CHOL	DFS	Median	All	0.221	0.723	<.001	32	view →
TGCT	DFS	Median	All	0.712	0.901	.001	18	view →
COAD	DFS	Tertile	II,III,IV	0.534	0.692	.004	17	view →
KICH	OS	Quartile	III,IV	0.178	0.833	.009	16	view →
ACC	DFS	Tertile	All	0.314	0.704	.011	12	view →
MESO	OS	Median	IV	0.683	0.272	.031	10	view →
THCA	OS	Tertile	III,IV	0.974	0.711	.017	10	view →
STAD	DFS	Tertile	II,III,IV	0.307	0.469	.039	8	view →
THYM	DFS	Quartile	All	0.512	0.841	.015	7	view →
LUAD	DFS	Quartile	III,IV	0.772	0.556	.023	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

CCDC103–LGG (DFS)

Open the LGG breakdown →