CCDC102B

Across TCGA patient cohorts, CCDC102B mutation is significantly associated with the RNA expression of many other genes, with 3,323 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC102B-associated genes across cancer lineages are TRAIP, PAXIP1, and IQCC. Each is linked with CCDC102B in more than 3 cancer types. Because this analysis shows association rather than direction, both CCDC102B-to-partner and partner-to-CCDC102B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAIP grouped by CCDC102B-low versus CCDC102B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC102B→partner) and Y-score (partner→CCDC102B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRAIP →	+0.413	+1.676	.005	.001	3	4
UCEC	PAXIP1 →	+0.416	+1.893	<.001	<.001	3	3
UCEC	IQCC →	+0.415	+1.781	.001	.008	3	3
UCEC	C16orf91 →	+0.431	+3.098	<.001	<.001	3	3
UCEC	DVL2 →	+0.499	+2.496	<.001	<.001	3	3
UCEC	ZNF569 →	+0.364	+2.939	.004	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,323 associations by consensus.

TRAIP by CCDC102B expression — UCEC

Explore this box plot interactively →