CCDC102B

Across TCGA pan-cancer cohorts, CCDC102B RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CCDC102B’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CCDC102B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC102B is over-expressed in tumor, although a few such as KICH and LUSC show the opposite, repressed pattern.

HNSC, KIRC, and KICH are the cancer types where CCDC102B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC102B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	II,III,IV	+0.844	<.001	12	view →
KIRC	Female	III,IV	+1.152	<.001	11	view →
KICH	Female	All	−1.200	<.001	9	view →
LIHC	Female	All	+0.848	<.001	9	view →
LUSC	Male	II,III,IV	−1.379	<.001	8	view →
LUAD	Female	II,III,IV	−1.108	<.001	8	view →
UCEC	All	All	−0.858	<.001	6	view →
THCA	All	All	−0.256	<.001	6	view →
CHOL	Male	All	+1.556	<.001	4	view →
STAD	All	II,III,IV	+0.469	.004	4	view →
READ	Male	All	+0.973	.044	2	view →
READ	Female	All	−0.866	.013	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 11 lineages.

CCDC102B–HNSC

Open the HNSC breakdown →