CBY2

Across TCGA cell cohorts, CBY2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,859 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CBY2-associated GO terms across cancer lineages are Regulation of DNA-templated transcription elongation, Regulation of protein localization to nucleus, and Regulation of transcription elongation by RNA polymerase II. Each is linked with CBY2 in more than 7 cancer types. Because this analysis shows association rather than direction, both CBY2-to-partner and partner-to-CBY2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA-templated transcription elongation grouped by CBY2-low versus CBY2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CBY2→partner) and Y-score (partner→CBY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of DNA-templated transcription elongation →	+0.064	+0.073	.001	.005	3	8
BONE	Regulation of protein localization to nucleus →	+0.058	+0.060	.001	.005	3	7
BONE	Regulation of transcription elongation by RNA polymerase II →	+0.059	+0.073	.003	.005	3	7
UPPER_AERODIGESTIVE_TRACT	mRNA transcription →	+0.053	+0.659	.005	<.001	3	7
LUNG_NSCLC_LUSC	mRNA destabilization →	+0.060	+0.573	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Negative regulation of DNA-templated transcription, elongation →	+0.101	+0.671	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,859 associations by consensus.

Regulation of DNA-templated transcription elongation by CBY2 expression — BONE

Explore this box plot interactively →