CBX1

Across TCGA patient cohorts, CBX1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,865 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CBX1-associated genes across cancer lineages are GKAP1, SALL2, and APBB1. Each is linked with CBX1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CBX1-to-partner and partner-to-CBX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBX1 versus GKAP1 in BRCA, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBX1→partner) and Y-score (partner→CBX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GKAP1 →	+0.639	+0.337	<.001	<.001	3	8
GBM	SALL2 →	+0.829	+0.313	<.001	<.001	3	6
UCEC	APBB1 →	+0.878	+0.216	<.001	<.001	3	6
HNSC	STAT5B →	+0.450	+0.394	.003	<.001	3	6
HNSC	ZNF181 →	+0.684	+0.455	<.001	<.001	3	6
CCRCC	GPRASP1 →	+0.632	+0.235	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,865 associations by consensus.

CBX1 vs GKAP1 — BRCA

Explore this scatter interactively →