CBWD2

Across TCGA patient cohorts, CBWD2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,596 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CBWD2-associated genes across cancer lineages are GHET1, PPP1R32, and TMEM182. Each is linked with CBWD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CBWD2-to-partner and partner-to-CBWD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBWD2 versus GHET1 in LSCC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBWD2→partner) and Y-score (partner→CBWD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GHET1 →	+0.527	+0.351	<.001	<.001	3	2
UCEC	PPP1R32 →	-1.045	-0.515	<.001	.008	3	2
UCEC	TMEM182 →	+0.490	+0.505	.008	.007	3	2
HNSC	RN7SKP43 →	+0.410	+0.918	.007	.002	3	2
CCRCC	C1orf21 →	-1.147	-0.846	.005	.008	3	2
LUAD	GYPC →	-0.423	-0.252	.003	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,596 associations by consensus.

CBWD2 vs GHET1 — LSCC

Explore this scatter interactively →