CBLIF

Across TCGA patient cohorts, CBLIF protein abundance is significantly associated with the RNA expression of many other genes, with 2,042 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CBLIF-associated genes across cancer lineages are SGPP1, KLHL35, and CFAP221. Each is linked with CBLIF in more than 1 cancer types. Because this analysis shows association rather than direction, both CBLIF-to-partner and partner-to-CBLIF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBLIF versus SGPP1 in HNSC, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBLIF→partner) and Y-score (partner→CBLIF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SGPP1 →	+1.274	+0.525	.004	.002	3	2
BRCA	KLHL35 →	+0.941	+0.647	.004	.004	3	2
PDAC	CFAP221 →	+1.144	+0.376	.005	.009	3	2
LUAD	PTGR1 →	-1.524	-0.386	.001	.002	3	2
GBM	ZFHX2 →	+0.799	+0.512	.003	.005	3	2
GBM	MET →	-1.665	-0.482	.009	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,042 associations by consensus.

CBLIF vs SGPP1 — HNSC

Explore this scatter interactively →