CBLIF

Across TCGA pan-cancer cohorts, CBLIF RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of CBLIF’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CBLIF RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CBLIF is over-expressed in tumor, although a few such as STAD and LUSC show the opposite, repressed pattern.

COAD, STAD, and BRCA are the cancer types where CBLIF tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CBLIF RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+1.101	<.001	9	view →
STAD	All	IV	−8.896	.001	6	view →
BRCA	Female	All	+0.043	.013	4	view →
LUSC	All	All	−0.021	.001	4	view →
READ	All	All	+0.633	.004	2	view →
KIRP	Female	All	+0.090	.025	2	view →
PRAD	All	All	+0.032	.041	2	view →
ESCA	All	All	−4.811	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

CBLIF–COAD

Open the COAD breakdown →