CBLIF

Across TCGA cell cohorts, CBLIF mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CBLIF-associated genes across cancer lineages are MS4A14, CABP2, and IFNW1. Each is linked with CBLIF in more than 1 cancer types. Because this analysis shows association rather than direction, both CBLIF-to-partner and partner-to-CBLIF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A14 grouped by CBLIF-low versus CBLIF-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBLIF→partner) and Y-score (partner→CBLIF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	MS4A14 →	+0.081	+4.930	<.001	.008	3	1
SOFT_TISSUE	CABP2 →	+0.092	+5.369	<.001	.004	3	1
SOFT_TISSUE	IFNW1 →	+0.015	+4.930	<.001	.008	3	1
SOFT_TISSUE	OR10Q1 →	+0.171	+4.930	<.001	.008	3	1
SOFT_TISSUE	RTL4 →	+0.039	+5.369	<.001	.004	3	1
SOFT_TISSUE	OR2T6 →	+0.012	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

MS4A14 by CBLIF expression — SOFT_TISSUE

Explore this box plot interactively →