CATSPERD

Across TCGA cell cohorts, CATSPERD mutation is significantly associated with the RNA expression of many other genes, with 227 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CATSPERD-associated genes across cancer lineages are XAGE5, FNDC3A, and FAM149A. Each is linked with CATSPERD in more than 1 cancer types. Because this analysis shows association rather than direction, both CATSPERD-to-partner and partner-to-CATSPERD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, XAGE5 grouped by CATSPERD-low versus CATSPERD-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CATSPERD→partner) and Y-score (partner→CATSPERD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	XAGE5 →	+0.255	+5.196	<.001	.005	3	1
LARGE_INTESTINE	FNDC3A →	+0.670	+3.212	<.001	.006	3	1
LARGE_INTESTINE	FAM149A →	+1.698	+3.212	<.001	.006	3	1
LARGE_INTESTINE	C1orf109 →	+0.754	+3.212	.002	.006	3	1
LARGE_INTESTINE	VPS4B →	+0.711	+3.212	.003	.006	3	1
LARGE_INTESTINE	DUSP4 →	+1.718	+3.212	.005	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 227 associations by consensus.

XAGE5 by CATSPERD expression — OVARY

Explore this box plot interactively →