CATSPERB

Across TCGA patient cohorts, CATSPERB mutation is significantly associated with the RNA expression of many other genes, with 4,262 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CATSPERB-associated genes across cancer lineages are ZNF408, ZNF569, and MT-ND6. Each is linked with CATSPERB in more than 2 cancer types. Because this analysis shows association rather than direction, both CATSPERB-to-partner and partner-to-CATSPERB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF408 grouped by CATSPERB-low versus CATSPERB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CATSPERB→partner) and Y-score (partner→CATSPERB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF408 →	+0.234	+1.490	.006	.001	3	3
UCEC	ZNF569 →	+0.358	+2.280	.002	<.001	3	3
UCEC	MT-ND6 →	-0.721	-1.989	<.001	.009	3	3
SKCM	MT-CYB →	-0.412	-1.328	.001	.006	3	3
UCEC	KLHL23 →	+0.503	+1.642	<.001	<.001	3	3
LIHC	MTCYBP44 →	+0.045	+5.584	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,262 associations by consensus.

ZNF408 by CATSPERB expression — UCEC

Explore this box plot interactively →