CATSPERB

Across TCGA pan-cancer cohorts, CATSPERB RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CATSPERB’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where CATSPERB RNA is repressed in tumor relative to normal tissue. In most cancer types CATSPERB is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KICH, and STAD are the cancer types where CATSPERB tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CATSPERB RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	III,IV	−0.259	<.001	10	view →
KICH	All	II,III,IV	−0.164	<.001	10	view →
STAD	All	All	+0.722	<.001	7	view →
BLCA	All	III,IV	+0.757	.005	5	view →
LUAD	Female	All	+0.565	<.001	4	view →
BRCA	All	II,III,IV	+0.424	.002	4	view →
CHOL	Male	All	+1.155	<.001	3	view →
LIHC	All	All	+0.182	.009	3	view →
BRCA	All	IV	−1.010	.006	2	view →
READ	All	II,III,IV	+0.605	.042	2	view →
UCEC	All	II,III,IV	+0.491	.043	2	view →
PRAD	All	All	+0.299	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 11 lineages.

CATSPERB–THCA

Open the THCA breakdown →