CATSPER4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CATSPER4 mutation is significantly associated with the RNA expression of many other genes, with 1,481 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CATSPER4-associated genes across cancer lineages are SEZ6L-AS1, TRAJ60, and SUMO2P7. Each is linked with CATSPER4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CATSPER4-to-partner and partner-to-CATSPER4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CATSPER4→partner) and Y-score (partner→CATSPER4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCSEZ6L-AS1 →+0.219+7.102<.001<.00132
COADTRAJ60 →+0.446+4.251<.001.00832
COADSUMO2P7 →+0.293+4.246<.001<.00132
COADLINC02598 →+0.437+3.933<.001.00432
COADKRT8P50 →+0.141+3.796.001.00532
UCECMIR6780B →+0.307+2.304<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,481 associations by consensus.

Exploration