CATSPER3

Across TCGA cell cohorts, CATSPER3 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CATSPER3-associated genes across cancer lineages are MS4A10, MAGEB4, and HPGDS. Each is linked with CATSPER3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CATSPER3-to-partner and partner-to-CATSPER3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A10 grouped by CATSPER3-low versus CATSPER3-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CATSPER3→partner) and Y-score (partner→CATSPER3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	MS4A10 →	+0.013	+5.196	<.001	.005	3	1
SKIN	MAGEB4 →	+0.008	+4.437	<.001	.004	3	1
SKIN	HPGDS →	+0.088	+3.823	<.001	.006	3	1
SKIN	KRTAP6-1 →	+0.060	+4.437	<.001	.004	3	1
SKIN	RTP2 →	+0.023	+4.217	<.001	.001	3	1
LARGE_INTESTINE	SLC15A5 →	+0.017	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

MS4A10 by CATSPER3 expression — OVARY

Explore this box plot interactively →