CASK-AS1

Across TCGA patient cohorts, CASK-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,832 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CASK-AS1-associated proteins across cancer lineages are CASK, EIF3A, and ZNF326. Each is linked with CASK-AS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CASK-AS1-to-partner and partner-to-CASK-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CASK-AS1 versus CASK in LSCC, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CASK-AS1→partner) and Y-score (partner→CASK-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CASK →	+0.460	+0.580	<.001	<.001	3	5
HNSC	EIF3A →	-0.168	-0.816	<.001	<.001	3	4
LSCC	ZNF326 →	+0.294	+0.390	.002	.003	3	3
LSCC	RCN2 →	+0.436	+0.395	<.001	<.001	3	3
LSCC	RPS6KA4 →	-0.322	-0.410	.001	.001	3	3
LSCC	SLC9A3R2 →	-0.268	-0.415	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,832 associations by consensus.

CASK-AS1 vs CASK — LSCC

Explore this scatter interactively →