CARNS1

Across TCGA cell cohorts, CARNS1 mutation is significantly associated with the RNA expression of many other genes, with 214 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CARNS1-associated genes across cancer lineages are SFTPB, FAM24A, and CENPVL1. Each is linked with CARNS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CARNS1-to-partner and partner-to-CARNS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SFTPB grouped by CARNS1-low versus CARNS1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CARNS1→partner) and Y-score (partner→CARNS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SFTPB →	+0.189	+2.770	<.001	.004	3	2
BLOOD_Leukemia	FAM24A →	+0.042	+3.969	<.001	.009	3	1
BLOOD_Leukemia	CENPVL1 →	+0.431	+4.556	<.001	<.001	3	1
BLOOD_Leukemia	TEX51 →	+0.286	+3.969	<.001	.009	3	1
BLOOD_Leukemia	KLF14 →	+0.067	+3.469	<.001	.004	3	1
BLOOD_Leukemia	LYZL6 →	+0.019	+3.969	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 214 associations by consensus.

SFTPB by CARNS1 expression — LARGE_INTESTINE

Explore this box plot interactively →