CARD18

Across TCGA patient cohorts, CARD18 protein abundance is significantly associated with the RNA expression of many other genes, with 4,232 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CARD18-associated genes across cancer lineages are SLC1A1, CASP9, and STON2. Each is linked with CARD18 in more than 1 cancer types. Because this analysis shows association rather than direction, both CARD18-to-partner and partner-to-CARD18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CARD18 versus SLC1A1 in HNSC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CARD18→partner) and Y-score (partner→CARD18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SLC1A1 →	-0.975	-1.395	<.001	<.001	3	2
HNSC	CASP9 →	-0.568	-1.142	.002	.002	3	2
LSCC	STON2 →	+1.427	+1.876	<.001	.006	3	2
LSCC	GLT1D1 →	-1.100	-2.347	<.001	<.001	3	2
LSCC	TMCO4 →	-0.698	-2.404	.001	<.001	3	2
HNSC	FLRT2 →	+0.882	+1.177	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,232 associations by consensus.

CARD18 vs SLC1A1 — HNSC

Explore this scatter interactively →