CARD18

Across TCGA pan-cancer cohorts, CARD18 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of CARD18’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where CARD18 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CARD18 is over-expressed in tumor.

LUSC, LIHC, and LUAD are the cancer types where CARD18 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CARD18 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	+1.340	<.001	6	view →
LIHC	All	All	+0.292	<.001	6	view →
LUAD	All	All	+0.108	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

CARD18–LUSC

Open the LUSC breakdown →