CARD18

Across TCGA cell cohorts, CARD18 RNA expression is significantly associated with the go_rna of many other GO terms, with 826 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible CARD18-associated GO terms across cancer lineages are Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, Tie signaling pathway, and Mesenchymal cell migration. Each is linked with CARD18 in more than 4 cancer types. Because this analysis shows association rather than direction, both CARD18-to-partner and partner-to-CARD18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway grouped by CARD18-low versus CARD18-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CARD18→partner) and Y-score (partner→CARD18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway →	-0.082	-0.564	<.001	.003	3	5
BLOOD_Myeloma	Tie signaling pathway →	+1.088	+0.726	.001	.002	3	5
LUNG_SCLC	Mesenchymal cell migration →	-0.062	-0.554	.001	.008	3	3
LIVER	Regulation of presynapse organization →	-0.145	-0.925	.003	.003	3	3
LIVER	Ribose phosphate biosynthetic process →	+0.054	+1.014	.006	.007	3	3
LIVER	Gamma-aminobutyric acid signaling pathway →	-0.286	-1.288	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 826 associations by consensus.

Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway by CARD18 expression — LUNG_SCLC

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