CARD14

Across TCGA cell cohorts, CARD14 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,438 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CARD14-associated GO terms across cancer lineages are Xenophagy, Negative regulation of autophagy, and Negative regulation of non-canonical Wnt signaling pathway. Each is linked with CARD14 in more than 9 cancer types. Because this analysis shows association rather than direction, both CARD14-to-partner and partner-to-CARD14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Xenophagy grouped by CARD14-low versus CARD14-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CARD14→partner) and Y-score (partner→CARD14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Xenophagy →	+0.228	+0.691	<.001	.002	3	10
BREAST	Negative regulation of autophagy →	+0.076	+1.974	<.001	<.001	3	10
OVARY	Negative regulation of non-canonical Wnt signaling pathway →	+0.184	+0.822	<.001	<.001	3	10
BREAST	Mycotoxin metabolic process →	-0.267	-2.347	<.001	<.001	3	10
BREAST	Aflatoxin metabolic process →	-0.267	-2.347	<.001	<.001	3	10
OVARY	Vacuolar transport →	+0.073	+1.024	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,438 associations by consensus.

Xenophagy by CARD14 expression — BLOOD_Lymphoma

Explore this box plot interactively →