CAPZB

Across TCGA patient cohorts, CAPZB protein abundance is significantly associated with the RNA expression of many other genes, with 21,788 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CAPZB-associated genes across cancer lineages are CYTH4, NCF4, and BTK. Each is linked with CAPZB in more than 8 cancer types. Because this analysis shows association rather than direction, both CAPZB-to-partner and partner-to-CAPZB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPZB versus CYTH4 in GBM, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPZB→partner) and Y-score (partner→CAPZB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYTH4 →	+0.949	+0.225	<.001	<.001	3	9
HNSC	NCF4 →	+1.039	+0.176	<.001	<.001	3	9
HNSC	BTK →	+0.941	+0.200	<.001	<.001	3	9
HNSC	IL10RA →	+1.033	+0.188	<.001	<.001	3	9
HNSC	NCKAP1L →	+1.164	+0.191	<.001	<.001	3	9
COAD	LSP1 →	+0.666	+0.129	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,788 associations by consensus.

CAPZB vs CYTH4 — GBM

Explore this scatter interactively →