CAPS

Across TCGA patient cohorts, CAPS protein abundance is significantly associated with the RNA expression of many other genes, with 16,798 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CAPS-associated genes across cancer lineages are MORN5, NWD1, and CAPSL. Each is linked with CAPS in more than 7 cancer types. Because this analysis shows association rather than direction, both CAPS-to-partner and partner-to-CAPS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPS versus MORN5 in OV, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPS→partner) and Y-score (partner→CAPS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MORN5 →	+1.458	+1.381	.004	<.001	3	8
UCEC	NWD1 →	+1.269	+0.931	<.001	<.001	3	7
OV	CAPSL →	+1.647	+1.025	<.001	<.001	3	7
UCEC	CFAP43 →	+1.978	+0.977	<.001	<.001	3	7
UCEC	C6orf118 →	+1.330	+0.723	<.001	<.001	3	6
UCEC	ADGB →	+1.414	+0.878	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,798 associations by consensus.

CAPS vs MORN5 — OV

Explore this scatter interactively →