CAPN5

Across TCGA patient cohorts, CAPN5 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,562 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CAPN5-associated proteins across cancer lineages are SH3BGRL2, PLS1, and MISP. Each is linked with CAPN5 in more than 5 cancer types. Because this analysis shows association rather than direction, both CAPN5-to-partner and partner-to-CAPN5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAPN5 versus SH3BGRL2 in HNSC, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN5→partner) and Y-score (partner→CAPN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SH3BGRL2 →	+0.566	+0.795	<.001	<.001	3	6
LSCC	PLS1 →	+0.630	+0.653	<.001	<.001	3	6
UCEC	MISP →	+0.791	+0.808	<.001	.006	3	5
UCEC	VILL →	+0.883	+1.285	<.001	<.001	3	4
LSCC	BCAS1 →	+1.211	+0.768	<.001	<.001	3	4
PDAC	C9orf152_S88 →	+0.880	+0.988	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,562 associations by consensus.

CAPN5 vs SH3BGRL2 — HNSC

Explore this scatter interactively →