CAPN5

Across TCGA cell cohorts, CAPN5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,423 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CAPN5-associated GO terms across cancer lineages are Macroautophagy, Cytosolic transport, and Negative regulation of protein-containing complex assembly. Each is linked with CAPN5 in more than 13 cancer types. Because this analysis shows association rather than direction, both CAPN5-to-partner and partner-to-CAPN5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by CAPN5-low versus CAPN5-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN5→partner) and Y-score (partner→CAPN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.080	+1.550	<.001	<.001	3	14
URINARY_TRACT	Cytosolic transport →	+0.062	+1.786	<.001	<.001	3	14
BONE	Negative regulation of protein-containing complex assembly →	+0.100	+1.438	<.001	<.001	3	14
BONE	Process utilizing autophagic mechanism →	+0.059	+1.261	<.001	<.001	3	13
BONE	Autophagy →	+0.059	+1.261	<.001	<.001	3	13
BONE	Golgi vesicle transport →	+0.064	+1.358	.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,423 associations by consensus.

Macroautophagy by CAPN5 expression — UPPER_AERODIGESTIVE_TRACT

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