CAPN10

Across TCGA patient cohorts, CAPN10 mutation is significantly associated with the RNA expression of many other genes, with 1,804 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAPN10-associated genes across cancer lineages are RNU6-1204P, RPL23AP4, and LINC02500. Each is linked with CAPN10 in more than 2 cancer types. Because this analysis shows association rather than direction, both CAPN10-to-partner and partner-to-CAPN10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1204P grouped by CAPN10-low versus CAPN10-high in KIRC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAPN10→partner) and Y-score (partner→CAPN10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	RNU6-1204P →	+0.223	+8.025	<.001	.007	3	3
SKCM	RPL23AP4 →	+0.079	+2.407	.001	.002	3	3
SKCM	LINC02500 →	+0.067	+3.750	<.001	.001	3	3
CESC	CHEK2P5 →	+0.146	+4.669	<.001	.007	3	2
CESC	RPS15AP34 →	+0.152	+5.196	<.001	.001	3	2
UCEC	RPL23AP82 →	+0.355	+2.721	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,804 associations by consensus.

RNU6-1204P by CAPN10 expression — KIRC

Explore this box plot interactively →