CAND1

Across TCGA patient cohorts, CAND1 mutation is significantly associated with the RNA expression of many other genes, with 3,542 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAND1-associated genes across cancer lineages are RPL32P4, DUXAP2, and SENP3-EIF4A1. Each is linked with CAND1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CAND1-to-partner and partner-to-CAND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL32P4 grouped by CAND1-low versus CAND1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAND1→partner) and Y-score (partner→CAND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RPL32P4 →	+0.157	+3.593	.004	.004	3	3
HNSC	DUXAP2 →	+0.209	+2.618	<.001	.008	3	3
UCEC	SENP3-EIF4A1 →	+0.079	+1.468	.001	.005	2	4
COAD	MIR548AL →	+0.088	+4.275	<.001	.004	3	3
UCEC	PTP4A3 →	-0.681	-3.311	<.001	<.001	3	3
UCEC	SORCS2 →	-0.567	-2.384	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,542 associations by consensus.

RPL32P4 by CAND1 expression — LIHC

Explore this box plot interactively →