CAMTA1

Across TCGA cell cohorts, CAMTA1 mutation is significantly associated with the RNA expression of many other genes, with 1,753 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CAMTA1-associated genes across cancer lineages are METTL4, THNSL2, and CFAP53. Each is linked with CAMTA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAMTA1-to-partner and partner-to-CAMTA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, METTL4 grouped by CAMTA1-low versus CAMTA1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMTA1→partner) and Y-score (partner→CAMTA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	METTL4 →	+0.564	+2.043	<.001	.001	3	2
SKIN	THNSL2 →	+1.641	+3.234	.001	.004	3	2
LARGE_INTESTINE	CFAP53 →	+0.404	+2.064	.001	.004	3	2
LARGE_INTESTINE	CST3 →	-0.947	-2.459	<.001	<.001	3	2
LARGE_INTESTINE	USP14 →	+0.585	+3.409	.001	<.001	3	2
LARGE_INTESTINE	SMCHD1 →	+0.924	+3.584	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,753 associations by consensus.

METTL4 by CAMTA1 expression — LARGE_INTESTINE

Explore this box plot interactively →