CAMKK2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CAMKK2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,036 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CAMKK2-associated genes across cancer lineages are LARP6, TREM1, and PTPN11. Each is linked with CAMKK2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CAMKK2-to-partner and partner-to-CAMKK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CAMKK2 versus LARP6 in GBM, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMKK2→partner) and Y-score (partner→CAMKK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMLARP6 →+0.824+0.481<.001<.00134
COADTREM1 →+0.896+0.216<.001<.00134
BRCAPTPN11 →+0.471+0.189.002.00234
BRCAC12orf76 →+0.376+0.193<.001.00234
BRCAKCTD10 →+0.416+0.231<.001.00133
BRCARSRC2 →+0.290+0.163<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,036 associations by consensus.

CAMKK2 vs LARP6 — GBM

Per-sample scatter of CAMKK2 vs LARP6 in GBM (Pearson r = 0.53).

Explore this scatter interactively →

Exploration